Detailed Product Description

Packing: 5g/piece, 20 g/piece, 100 g/piece

Specification: 5%, 10%, 20%, and 30%

Packing: 2-10ml ampoule or 5-30, 50ml, 100ml bottle

IUPAC name:

4-Methoxy-6-sulfanilamidopyrimidine sodium salt

CAS No: 1037-50-9

Molecular Formula: (C6H10-nO5)7(C₄H₈SO₃Na⁺)_n 

Molecular weight: average 2163 (based on average degree of substitution of 6.5)

Standard: the Company quality standard of Sulfobutyl Ether-β-Cyclodextrin Sodium Salt (2007)

Indications: N/A

Use:

SBE7-β-CD is a sulfobutyl ether derivative of β-cyclodextrin with an average of seven sulfobutyl ether groups per cyclodextrin molecule. Because of the very low pKa of the sulfonic acid groups, SBE7-β-CD carries multiple negative charges at physiologically compatible pH values. The four-carbon butyl chain coupled with repulsion of the end group negative charges allows for an "extension" of the cyclodextrin cavity. This often results in stronger binding to drug candidates than seen with other modified cyclodextrins. In addition, these derivatives impart exceptional solubility and parenteral safety to the molecule. In general, SBE7-β-CD will complex with many hydrophobic compounds that have structural features that can fit within the cyclodextrin cavity. A significant amount of literature is available illustrating the types of compounds that are candidates for inclusion complexation, but confirmation must be made by conducting a few simple laboratory tests. SBE7-β-CD will complex with peptides and proteins, can be used in injectable formulations, can be given by non-parenteral routes and is suitable for use in solid formulations.

Pharmacological action: N/A

Side effect and contraindication: N/A